Sodium Azide → HCID 13536743, compound
Reaction equation
Cl[CH2:2][C:3]([C:5]1[CH:6]=[CH:7][C:8]2[O:12][C:11]([CH3:14])([CH3:13])[S:10][C:9]=2[CH:15]=1)=[O:4].[N-:16]=[N+:17]=[N-:18].[Na+]>C(#N)C>[N:16]([CH2:2][C:3]([C:5]1[CH:6]=[CH:7][C:8]2[O:12][C:11]([CH3:14])([CH3:13])[S:10][C:9]=2[CH:15]=1)=[O:4])=[N+:17]=[N-:18]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of 20 g of 5-chloroacetyl-2,2-dimethyl-1,3-benzoxathiole (VII) in acetonitrile (100 ml) was stirred for two days with 7 g of finely powdered sodium azide. The reaction mixture was filtered, evaporated and the residue recrystallized from methanol to yield 12 g of 5-azidoacetyl-2,2-dimethyl-1,3-benzoxathiole (VIII), m.p. 52°-53° C.
Workup
- filtrationThe reaction mixture was filtered
- customevaporated
- customthe residue recrystallized from methanol
Sources & evidence
- ORD record
- ord-7c2d3559475148de8b9b252d33a9e813
- Source dataset
- uspto-grants-1985_10
- Patent number
- US04548951
Reaction notes
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