Trifop → HCID 13505617, compound

HRID 464912

Reaction equation

HRID 464912 reaction equation
[F:1][C:2]([F:23])([F:22])[C:3]1[CH:21]=[CH:20][C:6]([O:7][C:8]2[CH:19]=[CH:18][C:11]([O:12][CH:13]([CH3:17])[C:14](O)=[O:15])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.[Cl:24][C:25]1[CH:30]=[CH:29][C:28]([Cl:31])=[CH:27][C:26]=1[S:32]([N:35]=C=O)(=[O:34])=[O:33]>>[Cl:24][C:25]1[CH:30]=[CH:29][C:28]([Cl:31])=[CH:27][C:26]=1[S:32]([NH:35][C:14](=[O:15])[CH:13]([O:12][C:11]1[CH:10]=[CH:9][C:8]([O:7][C:6]2[CH:20]=[CH:21][C:3]([C:2]([F:23])([F:1])[F:22])=[CH:4][CH:5]=2)=[CH:19][CH:18]=1)[CH3:17])(=[O:33])=[O:34]

Participants

3

Reactant 2

HCID 181206TrifopHCID 128751872,5-Dichlorobenzene-1-sulfonyl isocyanate

Product 1

HCID 13505617HCID 13505617, compound

Procedure

A solution of one gram (0.0031 mole) 2-[4-(4-trifluoromethylphenoxy)phenoxy]-propionic acid in dry CHCH3 was treated with 0.8 gram (g) (0.0081 mole) 2,5-dichlorobenzene sulfonyl isocyanate. The solution was stirred for approximately 18 hours, then heated to reflux for three hours, followed by cooling.

Workup

  1. temperatureheated
  2. temperatureto reflux for three hours
  3. temperatureby cooling

Sources & evidence

ORD record
ord-1964ed97a263462cb25e4e9a6d4bd11f
Source dataset
uspto-grants-1985_10
Patent number
US04549901

Linked notes

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