[2-(3-Aminoprop-1-yn-1-yl)-5-chlorophenyl](2-chlorophenyl)methanone → HCID 20261332, compound

Reaction equation

[NH2:1][CH2:2][C:3]#[C:4][C:5]1[CH:10]=[CH:9][C:8](Cl)=[CH:7][C:6]=1[C:12](=[O:20])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[Cl:19].NCC#CC1C=CC([Cl:31])=CC=1C(=O)C1C=CC=CC=1>>[NH2:1][CH2:2][C:3]#[C:4][C:5]1([Cl:31])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]1[C:12](=[O:20])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[Cl:19]

Participants

Reactant 2

HCID 12948267[2-(3-Aminoprop-1-yn-1-yl)-5-chlorophenyl](2-chlorophenyl)methanone

HCID 12948268[2-(3-Aminoprop-1-yn-1-yl)-5-chlorophenyl](phenyl)methanone

Product 1

HCID 20261332HCID 20261332, compound

Procedure

The preparation of 3-amino-1-[4-chloro-2-(2-chlorobenzoyl)phenyl]propyne was conducted in the same manner as the preparation of 3-amino-1-[4-chloro-2-benzoylphenyl]propyne [Method A] to give pale yellow prisms, mp 81°-82° C.

Workup

customto give pale yellow prisms, mp 81°-82° C.

Sources & evidence

ORD record: ord-25393b19973643ac8bf36f1f598aed28
Source dataset: uspto-grants-1985_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04549988

Reaction notes

Loading…