N,N-Diethyl-2-piperidinemethanamine → HCID 13578557, compound

HRID 465060

Reaction equation

HRID 465060 reaction equation
[O:1]=[C:2]([N:5]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[C:9](=[O:16])[NH:8][C:7]2[CH:17]=[CH:18][CH:19]=[CH:20][C:6]1=2)[CH:3]=[CH2:4].[CH2:21]([N:23]([CH2:26][CH:27]1[CH2:32][CH2:31][CH2:30][CH2:29][NH:28]1)[CH2:24][CH3:25])[CH3:22]>>[CH2:21]([N:23]([CH2:26][CH:27]1[CH2:32][CH2:31][CH2:30][CH2:29][N:28]1[CH2:4][CH2:3][C:2]([N:5]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[C:9](=[O:16])[NH:8][C:7]2[CH:17]=[CH:18][CH:19]=[CH:20][C:6]1=2)=[O:1])[CH2:24][CH3:25])[CH3:22]

Participants

3

Reactant 2

HCID 254287N,N-Diethyl-2-piperidinemethanamineHCID 128347105-acryloyl-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one

Product 1

HCID 13578557HCID 13578557, compound

Procedure

The title compound is prepared analogously to Example 1h from 5,10-dihydro-5-(1-oxopropen-1-yl)-11H-dibenzo[b,e][1,4]diazepin-11-one and 2-[(diethylamino)methyl]piperdine to give colorless crystals mp. 125°-127° C. (acetonitrile).

Sources & evidence

ORD record
ord-bf78ab9571594bb0839ee52c8a32c320
Source dataset
uspto-grants-1985_10
Patent number
US04550107

Linked notes

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