2(1H)-Quinoxalinone → HCID 15667664, compound

HRID 465331

Reaction equation

HRID 465331 reaction equation
[NH:1]1[C:10]2C(=CC=CC=2)N=CC1=O.[N+:12]([C:15]1[CH:16]=[C:17]2[C:22](=[CH:23][CH:24]=1)[NH:21][C:20](=O)[CH:19]=[N:18]2)([O-:14])=[O:13].[N+:26]([O-])([O-])=O.[K+]>OS(O)(=O)=O>[N+:12]([C:15]1[CH:16]=[C:17]2[C:22](=[CH:23][CH:24]=1)[N:21]1[CH:10]=[N:1][N:26]=[C:20]1[CH:19]=[N:18]2)([O-:14])=[O:13]

Participants

5

Reactant 3

HCID 145262(1H)-QuinoxalinoneHCID 24434Potassium NitrateHCID 10429196-Nitroquinoxalin-2-one

Product 1

HCID 15667664HCID 15667664, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

The procedure of Example I.D. was followed except the quinoxalin-2-one was converted to the 6-nitroquinoxalin-2-one by first dissolving in conc. H2SO4 and cooling in an ice bath, and adding KNO3 in 3 portions. The product was collected by conventional technique and subsequently converted to 2-hydrazino-6-nitroquinoxaline. This compound was reacted with triethylorthoformate as per Example I.D., yielding 7-nitro-1,2,4-triazolo[4,3-a]quinoxaline (16).

Workup

  1. temperaturecooling in an ice bath
  2. customThe product was collected by conventional technique

Sources & evidence

ORD record
ord-761e282b1c9f48be85ab9368316d359b
Source dataset
uspto-grants-1992_10
Patent number
US05153196

Linked notes

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