4-Ethoxybenzoyl Chloride → 2,4-Di(4-ethoxybenzoyloxy)pyridine

HRID 466120

Reaction equation

HRID 466120 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][NH:5][C:4](=[O:8])[CH:3]=1.[CH2:9]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](Cl)=[O:17])=[CH:14][CH:13]=1)[CH3:10]>>[CH2:9]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]([O:8][C:4]2[CH:3]=[C:2]([O:1][C:16](=[O:17])[C:15]3[CH:14]=[CH:13][C:12]([O:11][CH2:9][CH3:10])=[CH:20][CH:19]=3)[CH:7]=[CH:6][N:5]=2)=[O:17])=[CH:14][CH:13]=1)[CH3:10]

Participants

3

Reactant 2

HCID 1400594-Ethoxybenzoyl ChlorideHCID 546960044-Hydroxy-2(1H)-pyridinone

Product 1

HCID 198152442,4-Di(4-ethoxybenzoyloxy)pyridineYield 6%

Procedure

The general procedure of Example 16 was followed using 1.00 g of 4-hydroxy-2-pyridone and 3.32 g of 4-ethoxybenzoyl chloride to produce 220 mg of the title compound in a yield of 6%.

Sources & evidence

ORD record
ord-63737d7f9f35465297fea1b3a40be1bc
Source dataset
uspto-grants-1992_10
Patent number
US05155113

Linked notes

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