HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl isocyanate → 1-Allyl-3-butyl-3-(4-methyl-2-oxazolyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl isocyanate | HCID 15123 | — |
| Reactant | 2-Oxazolamine, N-butyl-4-methyl- | HCID 12295226 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-Allyl-3-butyl-3-(4-methyl-2-oxazolyl)urea | HCID 23468970 | — |
Reaction Steps
A solution of 2-butylamino-4-methyloxazole (12.0 g, 0.078 mol) and allyl isocyanate (6.46 g, 0.078 mol) in dry benzene was heated under reflux for 4 hours, and worked up as described in Example 3. The product was further purified by chromatography on a silica-gel column, eluting with a 1:1 mixture of benzene and ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04175131 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-13bc78d337a34709a28e20131cf08c96 |
| Source note | uspto-grants-1979_11 |