1,3-Dichloro-4,6-dinitrobenzene → 4,6-Dichlorobenzene-1,3-diamine

HRID 470061

Reaction equation

HRID 470061 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([N+:9]([O-])=O)=[CH:4][C:3]=1[N+:12]([O-])=O>CC#N>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([NH2:9])=[CH:4][C:3]=1[NH2:12]

Participants

3

Reactant 1

HCID 772861,3-Dichloro-4,6-dinitrobenzene

Product 1

HCID 33728694,6-Dichlorobenzene-1,3-diamine

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

4,6-Dichloro-benzene-1,3-diamine (D-2) was synthesized following the general scheme above starting from 1,5-dichloro-2,4-dinitro-benzene. Yield (95%). HPLC ret. time 1.88 min, 10-99% CH3CN, 5 min run; ESI-MS 177.1 m/z (MH+).

Workup

  1. customYield (95%)

Sources & evidence

ORD record
ord-b26f3590dedb4e62ba3bca723084e02a
Source dataset
uspto-grants-2014_01
Patent number
US08629162B2

Linked notes

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