1-Chloro-2-(diethylamine)ethane hydrochloride → 7,7-Dimethyl-2-phenyl-5-(2-diethylamino-ethyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione dihydrochloride

HRID 47114

Reaction equation

HRID 47114 reaction equation
[ClH:1].[CH3:2][C:3]1([CH3:24])[C:12](=[O:13])[CH:11]2[C:6](=[C:7]3[N:17]=[C:16]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:15]=[C:8]3[C:9](=[O:14])[CH2:10]2)[CH:5]=[N:4]1.Cl.[CH2:26]([N:28]([CH2:32][CH3:33])[CH2:29][CH2:30][Cl:31])[CH3:27]>>[ClH:31].[ClH:1].[CH3:2][C:3]1([CH3:24])[C:12](=[O:13])[CH:11]2[C:6](=[C:7]3[N:17]=[C:16]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:15]=[C:8]3[C:9](=[O:14])[CH:10]2[CH2:27][CH2:26][N:28]([CH2:32][CH3:33])[CH2:29][CH3:30])[CH:5]=[N:4]1

Participants

3

Reactant 2

HCID 133631-Chloro-2-(diethylamine)ethane hydrochlorideHCID 706104497,7-Dimethyl-2-phenyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione hydrochloride

Product 1

HCID 706106547,7-Dimethyl-2-phenyl-5-(2-diethylamino-ethyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione dihydrochloride

Procedure

Prepared analogous to Example 23 from 5.1 gm of 7,7-dimethyl-2-phenyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione hydrochloride and 3.4 gm of 2-diethylamino-ethyl chloride hydrochloride,

Sources & evidence

ORD record
ord-4edc3c4ecad848ae9fc31610cd8a2e8c
Source dataset
uspto-grants-1979_11
Patent number
US04176184

Linked notes

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