((1E)-prop-1-en-1-yl)boronic acid → N-(2-Cyano-4-(E)-prop-1-enylphenyl)sulfamide

HRID 471549

Reaction equation

HRID 471549 reaction equation
[C:1]([C:3]1[CH:8]=[C:7](Br)[CH:6]=[CH:5][C:4]=1[NH:10][S:11]([NH2:14])(=[O:13])=[O:12])#[N:2].[CH:15](/B(O)O)=[CH:16]\[CH3:17]>>[C:1]([C:3]1[CH:8]=[C:7](/[CH:15]=[CH:16]/[CH3:17])[CH:6]=[CH:5][C:4]=1[NH:10][S:11]([NH2:14])(=[O:13])=[O:12])#[N:2]

Participants

3

Reactant 2

HCID 6157276((1E)-prop-1-en-1-yl)boronic acidHCID 67402187N-(2-cyano-4-bromophenyl)sulfamide

Product 1

HCID 86657472N-(2-Cyano-4-(E)-prop-1-enylphenyl)sulfamide

Procedure

Prepared as in Example 77a from N-(2-cyano-4-bromophenyl)sulfamide (Example 83b) and (E)-prop-1-enylboronic acid.

Sources & evidence

ORD record
ord-9488c07b377a4507bb19ea3327770ff8
Source dataset
uspto-grants-2014_01
Patent number
US08633186B2

Linked notes

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