Methylpropanediol → 2-(3-Hydroxy-2-methylpropoxy)-6-nitrobenzonitrile

HRID 471728

Reaction equation

[CH3:1][CH:2]([CH2:5][OH:6])[CH2:3][OH:4].[N+:7]([C:10]1[CH:17]=[CH:16][CH:15]=[C:14]([N+]([O-])=O)[C:11]=1[C:12]#[N:13])([O-:9])=[O:8]>>[OH:4][CH2:3][CH:2]([CH3:1])[CH2:5][O:6][C:14]1[CH:15]=[CH:16][CH:17]=[C:10]([N+:7]([O-:9])=[O:8])[C:11]=1[C:12]#[N:13]

Participants

Reactant 2

HCID 75103Methylpropanediol

HCID 520718Dinitrobenzonitrile

Product 1

HCID 673988582-(3-Hydroxy-2-methylpropoxy)-6-nitrobenzonitrileYield 37%

Procedure

Prepared as in Example 215c from 2-methylpropane-1,3-diol and 2,6-dinitrobenzonitrile in 37% yield. MS 237 (MH+).

Sources & evidence

ORD record: ord-e4e3ad52a7f14c1cbf08e9e8f78f728a
Source dataset: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08633186B2

Linked notes

Loading…