tert-Butyl Formate → HCID 66745961, compound

HRID 471766

Reaction equation

HRID 471766 reaction equation
[C:1]([C:3]1[C:23]([N+:24]([O-])=O)=[CH:22][CH:21]=[CH:20][C:4]=1[O:5][CH2:6][CH:7]1[CH2:12][CH2:11][CH2:10][N:9]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:8]1)#[N:2].C(OC(C)(C)C)=O>>[NH2:24][C:23]1[C:3]([C:1]#[N:2])=[C:4]([CH:20]=[CH:21][CH:22]=1)[O:5][CH2:6][CH:7]1[CH2:12][CH2:11][CH2:10][N:9]([C:13]([O:15][C:16]([CH3:19])([CH3:17])[CH3:18])=[O:14])[CH2:8]1

Participants

3

Reactant 2

HCID 61207tert-Butyl FormateHCID 66746046Tert-butyl 3-((2-cyano-3-nitrophenoxy)methyl)piperidine-1-carboxylate

Product 1

HCID 66745961HCID 66745961, compoundYield 100%

Procedure

Prepared as in example 254b from tert-butyl 3-((2-cyano-3-nitrophenoxy)methyl)piperidine-1-carboxylate (Example 262e) in 100% yield as an oil. MS 232 [M+H-Boc]+.

Sources & evidence

ORD record
ord-1a782fd57e0b4912a0d6ec400fbd335c
Source dataset
uspto-grants-2014_01
Patent number
US08633186B2

Linked notes

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