3-Chloro-5-cyanopyridine-2-carboxylic acid → 3-Chloro-5-cyanopicolinamide

HRID 474132

Reaction equation

HRID 474132 reaction equation
[Cl:1][C:2]1[C:3]([C:10]([OH:12])=O)=[N:4][CH:5]=[C:6]([C:8]#[N:9])[CH:7]=1.C(C1C=C(C)C(C(N)=O)=NC=1)#[N:14]>>[Cl:1][C:2]1[C:3]([C:10]([NH2:14])=[O:12])=[N:4][CH:5]=[C:6]([C:8]#[N:9])[CH:7]=1

Participants

3

Reactant 2

HCID 508531763-Chloro-5-cyanopyridine-2-carboxylic acidHCID 666659355-Cyano-3-methyl-2-pyridinecarboxamide

Product 1

HCID 674672293-Chloro-5-cyanopicolinamide

Procedure

3-Chloro-5-cyano-pyridine-2-carboxylic acid amide was prepared from 3-chloro-5-cyano-pyridine-2-carboxylic acid (CAS 1200497-81-9) in analogy to the procedure described for Amide 1.

Sources & evidence

ORD record
ord-32efe9f1ce9844dc9bb1b36930082a5e
Source dataset
uspto-grants-2014_01
Patent number
US08637508B2

Linked notes

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