Glyoxylic Acid → 4-(3,4-dimethoxyphenyl)-8-iodo-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid

Reaction equation

[I:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].[C:9]([OH:13])(=[O:12])[CH:10]=O.[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][C:23]=1[O:24][CH3:25])[CH:19]=[CH2:20]>>[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:19]2[C:5]3[C:3](=[C:2]([I:1])[CH:8]=[CH:7][CH:6]=3)[NH:4][CH:10]([C:9]([OH:13])=[O:12])[CH2:20]2)[CH:21]=[CH:22][C:23]=1[O:24][CH3:25]