Glyoxylic Acid → 4-(2,4-Dimethoxy-3-methylphenyl)-6-phenoxy-1,2,3,4-tetrahydroquinoline-2-carboxylic acid

HRID 47419

Reaction equation

HRID 47419 reaction equation
[O:1]([C:8]1[CH:14]=[CH:13][C:11]([NH2:12])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:15]([OH:19])(=[O:18])[CH:16]=O.[CH3:20][O:21][C:22]1[C:29]([CH3:30])=[C:28]([O:31][CH3:32])[CH:27]=[CH:26][C:23]=1[CH:24]=[CH2:25]>>[CH3:20][O:21][C:22]1[C:29]([CH3:30])=[C:28]([O:31][CH3:32])[CH:27]=[CH:26][C:23]=1[CH:24]1[C:10]2[C:11](=[CH:13][CH:14]=[C:8]([O:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH:9]=2)[NH:12][CH:16]([C:15]([OH:19])=[O:18])[CH2:25]1

Participants

4

Procedure

Compound 75 was prepared from 4-phenoxyaniline, glyoxylic acid and 2,4-dimethoxy-3-methylstyrene by the automated process.

Sources & evidence

ORD record
ord-81ef6dc20b354bc3a9b9b6e26e1453ee
Source dataset
uspto-grants-2004_03
Patent number
US06699877B2

Linked notes

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