HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Chloro-4-fluorophenyl)acetic acid → {(7R)-7-[[(2-chloro-4-fluorophenyl)acetyl](methyl)amino]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Chloro-4-fluorophenyl)acetic acid | HCID 2725061 | — |
| Reactant | propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate | HCID 86655417 | — |
| Product | {(7R)-7-[[(2-chloro-4-fluorophenyl)acetyl](methyl)amino]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}acetic acid | HCID 54581747 | — |
Reaction Steps
The title compound was prepared using analogous procedures described in Example 1 (Method A) from (2-chloro-4-fluorophenyl)acetic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 429.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637671B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-daa015facb00488cb7d8001cd6a4772c |
| Source note | uspto-grants-2014_01 |