Methyl Salicylate → Trimethylolethane salicylate

HRID 477066

Reaction equation

HRID 477066 reaction equation
[C:1]([O:10]CC(CO)O)(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:16]([C:18]([CH2:22][OH:23])([CH2:20][OH:21])[CH3:19])[OH:17].C(OC)(=O)C1C(=CC=CC=1)O.C[O-].[Na+]>>[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:16]([C:18]([CH2:22][OH:23])([CH2:20][OH:21])[CH3:19])[OH:17]

Participants

5

Reactant 4

HCID 4133Methyl Salicylate2×HCID 6502TrimethylolethaneHCID 38493182,3-Dihydroxypropyl salicylateHCID 10942334Sodium Methoxide

Product 1

HCID 70390081Trimethylolethane salicylate

Procedure

Trimethylolethane salicylate was prepared by the method described in Example 1 for the preparation of glycerol salicylate except that the reactants were trimethylolethane (60.1 g; 0.5 moles), methyl salicylate (119.7 g; 0.788 moles), sodium methoxide (0.82 g; 0.015 moles). The final methyl salicylate level was 10.0%.

Sources & evidence

ORD record
ord-7cf1c8d830fe483db8fd085ee7f9672d
Source dataset
uspto-grants-1989_12
Patent number
US04886843

Linked notes

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