2-Nitrophenol → HCID 15017530, compound

HRID 477268

Reaction equation

HRID 477268 reaction equation
[Cl:1][C:2]1[C:3](F)=[N:4][CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[N+:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[OH:22])([O-:15])=[O:14]>>[Cl:1][C:2]1[C:3]([O:22][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[N+:13]([O-:15])=[O:14])=[N:4][CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1

Participants

3

Reactant 2

HCID 69472-NitrophenolHCID 12680753-Chloro-2-fluoro-5-(trifluoromethyl)pyridine

Product 1

HCID 15017530HCID 15017530, compoundYield 63%

Procedure

This material was prepared in 63% yield from 3-chloro-2-fluoro-5-trifluoromethylpyridine and 2-nitrophenol following the general procedure outlined in Example 104. The product was isolated as an amber oil which was characterized by IR and 1H NMR spectroscopy.

Workup

  1. customThe product was isolated as an amber oil which

Sources & evidence

ORD record
ord-ee74605885a04bcebaa429762abca957
Source dataset
uspto-grants-1989_12
Patent number
US04886883

Linked notes

Loading…