Dimethyl acetylenedicarboxylate → HCID 178498582, compound

HRID 477548

Reaction equation

HRID 477548 reaction equation
[NH2:1][C:2]1[N:6]=[C:5]([SH:7])[NH:4][N:3]=1.[C:8]([C:14](OC)=[O:15])#[C:9][C:10]([O:12][CH3:13])=[O:11]>C(O)C>[OH:15][C:14]1[N:6]2[C:5]([SH:7])=[N:4][N:3]=[C:2]2[N:1]=[C:9]([C:10]([O:12][CH3:13])=[O:11])[CH:8]=1

Participants

4

Reactant 2

HCID 12980Dimethyl acetylenedicarboxylateHCID 1785092965-amino-1H-1,2,4-triazole-3-thiol

Product 1

HCID 178498582HCID 178498582, compoundYield 98.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 15.1 g of 3-amino-5-mercapto-s-triazole, 18.9 g of dimethyl acetylenedicarboxylate and 100 ml of ethanol was refluxed for 90 minutes. The objective compound (29 g) was obtained by collecting the crystals separated out upon cooling the reaction mixture.

Workup

  1. temperaturewas refluxed for 90 minutes

Sources & evidence

ORD record
ord-ab28199051994013806e59018bbb82ba
Source dataset
uspto-grants-1989_12
Patent number
US04888332

Linked notes

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