HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzeneacetic acid, 2-fluoro- → 2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzeneacetic acid, 2-fluoro- | HCID 67979 | — |
| Reactant | Isobutyl 2-aminobutyrate | HCID 13743360 | — |
| Product | 2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester | HCID 53643249 | — |
Reaction Steps
Following General Procedure I above and using 2-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was By filtration as described in the general procedure. NMR data was as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642261B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-68c4b4157d714eb5aed1f4de634e96ff |
| Source note | uspto-grants-2003_11 |