Cyanamide → N-cyano-N'-(2-fluorophenyl)thiourea

HRID 479517Notes

Reaction equation

[N:1]#[C:2][NH2:3].[F:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N:11]=[C:12]=[S:13]>>[C:2]([NH:3][C:12]([NH:11][C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=1[F:4])=[S:13])#[N:1]

Participants

Reactant 2

HCID 9864Cyanamide

HCID 975202-Fluorophenyl isothiocyanate

Product 1

HCID 18770560N-cyano-N'-(2-fluorophenyl)thiourea

Procedure

Cyanamide and 2-fluorophenyl isothiocyanate were processed as described in Example 44A to provide the desired product which was used without further purification.

Sources & evidence

ORD record: ord-680ce4bbf47a45de8019412d315ce022
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06645968B2

Reaction notes

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