HuagongsheHuagongshe Chemistry Print Report · For research reference only
Uridine → 5'-O-(4-Methylbenzoyl)uridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Uridine | HCID 6029 | — |
| Reactant | 4-Methylbenzoyl Chloride | HCID 13405 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 5'-O-(4-Methylbenzoyl)uridine | HCID 11588577 | — |
Reaction Steps
4-Methylbenzoyl chloride (10 mmol) is added to a solution of uridine (10 mmol) in 20 mL of pyridine. After no further progress occurs as observed by TLC, the volatile components are evaporated in vacuo. The residue is purified using flash chromatography to give the product as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06702705B1 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-5fea9a53770246ee989f9ac9adc592d9 |
| Source note | uspto-grants-2004_03 |