(2S,3S)-3-(5-(1-Cyanocyclopropyl)-2-methoxybenzyl)amino-2-phenylpiperidine dihydrochloride → (2S,3S)-3-(5-(1-cyano-1-methylethyl)-2-methoxybenzyl)amino-2-phenylpiperidine Dihydrochloride

HRID 481505

Reaction equation

HRID 481505 reaction equation
C(C(C1C=CC(OC)=C(C=1)C=O)(C)C)#N.[ClH:16].Cl.C1([C@H]2[C@@H](N)CCCN2)C=CC=CC=1.Cl.Cl.[C:33]([C:35]1([C:38]2[CH:39]=[CH:40][C:41]([O:58][CH3:59])=[C:42]([CH:57]=2)[CH2:43][NH:44][C@H:45]2[CH2:50][CH2:49][CH2:48][NH:47][C@H:46]2[C:51]2[CH:56]=[CH:55][CH:54]=[CH:53][CH:52]=2)[CH2:37][CH2:36]1)#[N:34]>>[ClH:16].[ClH:16].[C:33]([C:35]([C:38]1[CH:39]=[CH:40][C:41]([O:58][CH3:59])=[C:42]([CH:57]=1)[CH2:43][NH:44][C@H:45]1[CH2:50][CH2:49][CH2:48][NH:47][C@H:46]1[C:51]1[CH:56]=[CH:55][CH:54]=[CH:53][CH:52]=1)([CH3:37])[CH3:36])#[N:34]

Participants

4

Procedure

This compound was prepared from Compound 27 and Compound 3 in the same manner of Compound 5.

Sources & evidence

ORD record
ord-191e4d2b724b4f72afb5ab1e78c87da6
Source dataset
uspto-grants-1998_08
Patent number
US05789423

Linked notes

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