HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-chloroethyl)-2,3-dihydro-4-methylpyrido[3,2-f][1,4]-oxazepine-5(4H)-one → 2-[(dimethylamino)methyl]2,3-dihydro-4-methylpyrido[3,2-f][1,4]oxazepin-5(4H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-chloroethyl)-2,3-dihydro-4-methylpyrido[3,2-f][1,4]-oxazepine-5(4H)-one | HCID 13726436 | — |
| Reactant | 2-chloromethyl-2,3-dihydro-4-methylpyrido[3,2-f][1,4]-oxazepin-5(4H)-one | HCID 21271588 | — |
| Product | 2-[(dimethylamino)methyl]2,3-dihydro-4-methylpyrido[3,2-f][1,4]oxazepin-5(4H)-one | HCID 13689429 | — |
Reaction Steps
When in the procedure of Example 10, 2-chloromethyl-2,3-dihydro-4-methylpyrido[3,2-f][1,4]-oxazepin-5(4H)-one is substituted for 2-(2-chloroethyl)-2,3-dihydro-4-methylpyrido[3,2-f][1,4]-oxazepin-5(4H)-one, the title compound is prepared and is isolated if desired as a pharmaceutically acceptable salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04727152 |
| Source dataset | uspto-grants-1988_02 |
| ORD ID | ord-f2ced41ca80546fca5cc841a48e387ac |
| Source note | uspto-grants-1988_02 |