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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 48416Generated: October 26, 2026

Formamide → HCID 178435036, compound

https://huagongshe.com/reaction/48416

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormamideHCID 713—
ReactantEthyl 2-amino-4,5-dimethyl3-thenoateHCID 78536—
ProductHCID 178435036HCID 178435036—

Reaction Steps

Using ethyl 2-amino-4,5-dimethylthiophene-3-carboxylate (500 mg, 2.5 mmol) and formamide (5 ml), a similar procedure to a) in Production Example 208 was carried out to obtain 4-hydroxy-5,6-dimethylthieno[2,3-d]pyrimidine (380 mg, 2.1 mmol) having the following physical properties:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06703421B1
Source datasetuspto-grants-2004_03
ORD IDord-46f90a519b5943e88f8d76ee4b2208df
Source noteuspto-grants-2004_03