2-Bromo-9H-fluorene → 2-(Chloroacetyl)-7-methylfluorene

HRID 484742

Reaction equation

HRID 484742 reaction equation
[Cl:1][CH2:2][C:3]([C:5]1[CH:17]=[CH:16][C:15]2[C:14]3[C:9](=[CH:10][C:11](Br)=[CH:12][CH:13]=3)[CH2:8][C:7]=2[CH:6]=1)=[O:4].Br[C:20]1C=CC2C3C(=CC=CC=3)CC=2C=1>>[Cl:1][CH2:2][C:3]([C:5]1[CH:17]=[CH:16][C:15]2[C:14]3[C:9](=[CH:10][C:11]([CH3:20])=[CH:12][CH:13]=3)[CH2:8][C:7]=2[CH:6]=1)=[O:4]

Participants

3

Reactant 2

HCID 143362-Bromo-9H-fluoreneHCID 20272029Ledipasvir Impurity 46

Product 1

HCID 136627072-(Chloroacetyl)-7-methylfluorene

Procedure

Following the same procedure, 2-(chloroacetyl)-7-bromofluorene was prepared from 2-bromofluorene.

Sources & evidence

ORD record
ord-39689da15e0244548020c3e6a702f065
Source dataset
uspto-grants-1985_08
Patent number
US04533670

Linked notes

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