Methanol → 5-Pentyl-1,3-oxazole-4-carboxylic acid
Reaction equation
[CH2:1]([C:6]1[O:10][CH:9]=[N:8][C:7]=1[C:11]([O:13]C)=[O:12])[CH2:2][CH2:3][CH2:4][CH3:5].[OH-].[K+].CO>O>[CH2:1]([C:6]1[O:10][CH:9]=[N:8][C:7]=1[C:11]([OH:13])=[O:12])[CH2:2][CH2:3][CH2:4][CH3:5]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
40 g of 5-n-pentyl-4-methoxycarbonyloxazole, 27 g of potassium hydroxide, 1000 ml of methanol and 50 ml of water are treated in the same manner as described in Preparation 1-(2). 29.7 g of 5-n-pentyl-4-oxazolecarboxylic acid are thereby obtained. Yield: 80%.
Workup
- customas described in Preparation 1-(2)
Sources & evidence
- ORD record
- ord-0d2201c0e0224408ae36aaaaca443ffb
- Source dataset
- uspto-grants-1985_08
- Patent number
- US04535089
Reaction notes
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