3-Bromoheptan-4-one → 4-Ethyl-5-methyl-1,3-thiazol-2-amine

Reaction equation

BrCC(=O)CCCCC.BrC(C(=O)CCC)CC.BrC(C(C)C)C(=O)C(C)C.NC1SC=C(CCCCC)N=1.[NH2:40][C:41]1[S:42][C:43]([CH2:48]CC)=[C:44]([CH2:46][CH3:47])[N:45]=1.NC1SC(C(C)C)=C(C(C)C)N=1>>[NH2:40][C:41]1[S:42][C:43]([CH3:48])=[C:44]([CH2:46][CH3:47])[N:45]=1

Participants

Reactant 6

HCID 114695933-Bromoheptan-4-one

HCID 124317341-Bromoheptan-2-one

HCID 133294812-Amino-4-pentylthiazole

HCID 138404444-Bromo-2,5-dimethyl-3-hexanone

HCID 202712142-Amino-4,5-diisopropylthiazole

HCID 202712632-Amino-4-ethyl-5-propylthiazole

Product 1

HCID 3164022

Procedure

By the same method, 1-bromo-2-heptanone, 3-bromo-4-heptanone and 4-bromo-2,5-dimethyl-3-hexanone are converted to 2-amino-4-pentylthiazole, 2-amino-4-ethyl-5-propylthiazole and 2-amino-4,5-diisopropylthiazole, respectively.