Indazolinone → HCID 178519539, compound

HRID 485746

Reaction equation

[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([OH:10])=[N:2]1.[CH2:11]([N:18]1C(=O)O[C:21](=[O:22])[C:20]2=[CH:26][CH:27]=[CH:28][CH:29]=[C:19]12)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH2:11]([NH:18][C:19]1[CH:29]=[CH:28][CH:27]=[CH:26][C:20]=1[C:21]([N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([OH:10])=[N:2]1)=[O:22])[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

Reactant 2

HCID 81829Indazolinone

HCID 520756N-Benzylisatoic anhydride

Product 1

HCID 178519539HCID 178519539, compoundYield 71.5%

Procedure

1H-Indazol-3-ol was reacted with N-benzylisatoic anhydride according to the general procedure A above and afforded the desired amine as a yellow solid in 71.5% yield; m.p. 163°-165° C.

Sources & evidence

ORD record: ord-70f241f597144e338e93f2c24a84d2d1
Source dataset: uspto-grants-1985_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04537966

Linked notes

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