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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 48632Generated: October 25, 2026

(+-)-Tetrahydropapaverine → 2-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-but-2-yl-acetamide

https://huagongshe.com/reaction/48632

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+-)-TetrahydropapaverineHCID 5418—
ReactantSec-ButylamineHCID 24874—
ReactantBromoacetyl bromideHCID 61147—
Product2-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-but-2-yl-acetamideHCID 22742766—

Reaction Steps

prepared by reaction of 1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 2-butylamine

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06703392B2
Source datasetuspto-grants-2004_03
ORD IDord-9ea72fc7f32549379a13237c566c1556
Source noteuspto-grants-2004_03