3,5-Dibromoaniline → 2-(3,5-Dibromophenyl)thiophene

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([Br:9])[CH:8]=1)N.BrC1C=C([C:17]2[S:18][CH:19]=[CH:20][CH:21]=2)C=CC=1>>[Br:1][C:2]1[CH:3]=[C:4]([C:17]2[S:18][CH:19]=[CH:20][CH:21]=2)[CH:6]=[C:7]([Br:9])[CH:8]=1

Participants

Reactant 2

HCID 2215123,5-Dibromoaniline

HCID 12060894HCID 12060894, compound

Product 1

HCID 190061762-(3,5-Dibromophenyl)thiopheneYield 55%

Procedure

3,5-dibromoaniline was treated as described in the procedure for 2-(3'-bromophenyl)thiophene to give 2-(3',5'-dibromophenyl)thiophene in 55% yield as a yellow oil, which solidified as a glassy solid.

Sources & evidence

ORD record: ord-916c752517944a3c98038f51122a7296
Source dataset: uspto-grants-1994_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05292879

Reaction notes

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