(4-Chloro-1,2-phenylene)dimethanol → 1,2-Benzenedimethanol

Reaction equation

C[CH:2]([CH:5]([OH:8])[CH2:6][Cl:7])[CH2:3][OH:4].Cl[C:10]1[CH:11]=[C:12]([CH2:18][OH:19])[C:13]([CH2:16][OH:17])=[CH:14][CH:15]=1>>[Cl:7][CH2:6][CH:5]([OH:8])[CH2:2][CH2:3][OH:4].[C:12]1([CH2:18][OH:19])[C:13]([CH2:16][OH:17])=[CH:14][CH:15]=[CH:10][CH:11]=1

Participants

Reactant 2

HCID 10899147(4-Chloro-1,2-phenylene)dimethanol

HCID 190917132-Methyl-4-chloro-1,3-butanediol

Product 2

HCID 691531,2-Benzenedimethanol

HCID 51529014-Chlorobutane-1,3-diol

Procedure

Example 1 was repeated except for using 10.53 g (76 mmoles) of 2-methyl-4-chloro-1,3-butanediol and 6.00 g (35 mmoles) of 4-chloro-o-xylylene glycol, instead of 9.48 g (76 mmoles of 4-chloro-1,3-butanediol and 4.76 g (35 mmoles) of o-xylylene glycol, respectively, to obtain spiro[7-chloro-1,5-dihydro-2,4-benzodioxepin-4'-methylene-5'-methyl-3,2'-[1,3dioxane.

Sources & evidence

ORD record: ord-ae2e8084b83e42abbde00fff1507fa06
Source dataset: uspto-grants-1994_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05298631

Reaction notes

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