Methyl 3-oxo-7,11,15-trimethylhexadeca-6,10,14-trienoate → [2-Hydroxy-6,10,14-trimethylpentadeca-5,9,13-trienyl]phosphonic acid

Participants

Reaction Steps

This compound was prepared similarly by the method described in Step 2 of Example 1 except that methyl 3-oxo-7,11,15-trimethylhexadeca-6,10,14-trienoate was replaced by dimethyl [2-oxo-6,10, 14-trimethyl-pentadeca-5,9,13-trienyl]phosphonate and the product from this reaction was used in the hydrolysis step similarly to the method used in Step 2 in Example 2 to give, after lyophilization, title compound as a nearly colorless gum.

Provenance & Evidence