2-Fluoroethyl bromide → 2-[1-(3,4-dimethoxy-benzyl)-5-(2-fluoro-ethoxy)-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide

Participants

Role	Name	HCID	Charge
Reactant	2-Fluoroethyl bromide	HCID 12982	—
Reactant	2-[1-(3,4-dimethoxy-benzyl)-5-hydroxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide	HCID 22742553	—
Product	2-[1-(3,4-dimethoxy-benzyl)-5-(2-fluoro-ethoxy)-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide	HCID 22742670	—

Reaction Steps

prepared by reaction of 2-[1-(3,4-dimethoxy-benzyl)-5-hydroxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide with 1-bromo-2-fluoro-ethane

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06703392B2
Source dataset	uspto-grants-2004_03
ORD ID	ord-381b45043cf7439c93f9a6227af00cb2
Source note	uspto-grants-2004_03