Methyl 2-[(2-methoxy-2-oxoethyl)amino]acetate → N-(2-methoxy-2-oxoethyl)-N-[3-(decyloxy)benzoyl]glycine methyl ester
Reaction equation
[CH2:1]([O:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[C:15]([OH:17])=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[NH:21]([CH2:27][C:28]([O:30][CH3:31])=[O:29])[CH2:22][C:23]([O:25][CH3:26])=[O:24]>>[CH3:31][O:30][C:28](=[O:29])[CH2:27][N:21]([CH2:22][C:23]([O:25][CH3:26])=[O:24])[C:15](=[O:17])[C:14]1[CH:18]=[CH:19][CH:20]=[C:12]([O:11][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH:13]=1Participants
3
Procedure
The conversion of 3-(decyloxy)benzoic acid to the acid chloride followed by treatment with dimethyl iminodiacetate as in Example 1 gave N-(2-methoxy-2-oxoethyl)-N-[3-(decyloxy)benzoyl]glycine methyl ester as an oil. The nmr and mass spectra were consistent with the structure.
Sources & evidence
- ORD record
- ord-dfdbe68aa60f44b6a54bc144dcc3aade
- Source dataset
- uspto-grants-1994_03