1-Iododecane → HCID 10387733, compound

HRID 488850

Reaction equation

HRID 488850 reaction equation
[I:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[NH2:12][C:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[N:16]=[C:15]([CH3:23])[CH:14]=1>C(C(C)=O)C>[I-:1].[CH2:2]([N+:16]1[C:17]2[C:22](=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:13]([NH2:12])=[CH:14][C:15]=1[CH3:23])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

Participants

4

Reactant 2

HCID 163141-IododecaneHCID 811164-Amino-2-methylquinoline

Product 1

HCID 10387733HCID 10387733, compound

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

This compound was prepared by mixing commercially available iododecane and 4-aminoquinaldine in methyl ethyl ketone, and refluxing for 72 h. The solid product was collected by filtration and recrystallized twice in absolute ethanol. 1H NMR (in DMSO-d6): δ 0.85 (t, J=5.1 Hz, 3H), 1.24 (br, 12H), 1.43 (m, 2H), 1.70 (m, 2H), 2.73 (s, 3H), 4.45 (t, J=8.09 Hz, 2H), 6.73 (s, 1H), 7.72 (dd, 1H), 8.02 (dd, 1H), 8.15 (d, J=8.94 Hz, 1H), 8.43 (d, J=8.37 Hz), 8.81 (br, 2H). Elemental analysis Calcd for C20H31N2I: C, 56.33%; H, 7.33%; N, 6.57%. Found: C, 56.23%; H, 7.41%; N, 6.42%. MS, [M-I−]=299 (m/z) (calcd 299.47 for C20H31N2).

Workup

  1. customThis compound was prepared
  2. temperaturerefluxing for 72 h
  3. filtrationThe solid product was collected by filtration
  4. customrecrystallized twice in absolute ethanol

Sources & evidence

ORD record
ord-4f46c5e1dc04483dbd980ffabe70d0de
Source dataset
uspto-grants-2005_12
Patent number
US06974871B2

Linked notes

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