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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4892Generated: October 26, 2026

8-(3-Aminopropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione → Theophylline

https://huagongshe.com/reaction/4892

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-(3-Aminopropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dioneHCID 13052008—
SolventCarbonate IonHCID 19660—
ProductTheophyllineHCID 2153—

Reaction Steps

A solution of 5 mM 8-(3-aminopropyl)-theophylline (R.C. Boguslaski et al., 1980) in 0.1 M carbonate buffer, pH 8.0, was incubated with an N-hydroxysuccinimide ester activated dextran surface (according to Example I.3.2) overnight at 25° C., whereupon the surface was washed with water.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05242828
Source datasetuspto-grants-1993_09
ORD IDord-fef06120f7244b028a882a59eab365e0
Source noteuspto-grants-1993_09