Methyl furan-3-carboxylate → 4-(2,1,3-benzoxadiazol-4-yl)-6-(furan-2-yl)-2,4-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

HRID 489385Notes

Reaction equation

HRID 489385 reaction equation
[O:1]1[CH:5]=[CH:4][C:3](C(OC)=O)=[CH:2]1.[N:10]1[O:11][N:12]=[C:13]2[C:18]([CH:19]=O)=[CH:17][CH:16]=[CH:15][C:14]=12.[NH2:21][C:22]1[CH:26]=[CH:25][NH:24][N:23]=1>>[N:10]1[O:11][N:12]=[C:13]2[C:18]([CH:19]3[C:13]([C:14]#[N:10])=[C:18]([C:2]4[O:1][CH:5]=[CH:4][CH:3]=4)[NH:21][C:22]4=[N:23][NH:24][CH:25]=[C:26]34)=[CH:17][CH:16]=[CH:15][C:14]=12

Participants

4

Reactant 3

HCID 14918Methyl furan-3-carboxylateHCID 102908732,1,3-Benzoxadiazole-4-carbaldehydeHCID 178418806HCID 178418806, compound

Product 1

HCID 1785093874-(2,1,3-benzoxadiazol-4-yl)-6-(furan-2-yl)-2,4-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

Procedure

The title compound was prepared from methyl furan-3-carboxylate, 2,1,3-benzoxadiazole-4-aldehyde and 3-aminopyrazole in the same manner as in Example 95.

Sources & evidence

ORD record
ord-c2539a1318e84583aff0c7fc138dc96f
Source dataset
uspto-grants-2005_12
Patent number
US06977262B2

Reaction notes

Loading…