HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4'-Dimethoxydiphenylamine → 4-Methoxy-N-(4-methoxyphenyl)-N-phenylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4'-Dimethoxydiphenylamine | HCID 7571 | — |
| Reactant | Iodobenzene | HCID 11575 | — |
| Reactant | sodium 2-methylpropan-2-olate | HCID 178418730 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 4-Methoxy-N-(4-methoxyphenyl)-N-phenylaniline | HCID 10543043 | — |
Reaction Steps
1.00 g (4.46 mmols) of N,N-di(4-methoxyphenyl)amine (31a), 1.00 g (4.90 mmols) of iodobenzene (32a), 0.502 g (5.23 mmols) of t-BuONa and 0.010 g (0.044 mmols) of Pd(CH3COO)2 were dissolved in anhydrous xylene, and while refluxing the solution in an atmosphere of nitrogen, 1.0 ml of 0.237 M of P(But)3 was further dropped, followed by refluxing for 4 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06979746B2 |
| Source dataset | uspto-grants-2005_12 |
| ORD ID | ord-1c9b7ed7850a4341956aa0d649b0ad8a |
| Source note | uspto-grants-2005_12 |