3-Formyl-2-methylindole → 3-(2-Methyl-1H-indol-3-ylmethylene)-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide

HRID 49098

Reaction equation

HRID 49098 reaction equation
[NH2:1][S:2]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[CH2:8]2)(=[O:4])=[O:3].[CH3:15][C:16]1[NH:17][C:18]2[C:23]([C:24]=1[CH:25]=O)=[CH:22][CH:21]=[CH:20][CH:19]=2>>[CH3:15][C:16]1[NH:17][C:18]2[C:23]([C:24]=1[CH:25]=[C:8]1[C:7]3[C:11](=[CH:12][CH:13]=[C:5]([S:2]([NH2:1])(=[O:4])=[O:3])[CH:6]=3)[NH:10][C:9]1=[O:14])=[CH:22][CH:21]=[CH:20][CH:19]=2

Participants

3

Reactant 2

HCID 731663-Formyl-2-methylindoleHCID 101982322-Oxoindoline-5-sulfonamide

Product 1

HCID 693448633-(2-Methyl-1H-indol-3-ylmethylene)-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide

Procedure

5-Aminosulfonyl-2-oxindole was condensed with 2-methylindole-3-carboxaldehyde to give the title compound.

Sources & evidence

ORD record
ord-e513d9d542a6480d8480ffa4bf363cc1
Source dataset
uspto-grants-2004_03
Patent number
US06706709B2

Linked notes

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