Ammonia → 3-Chloro-P-toluenesulfonamide

HRID 493058

Reaction equation

HRID 493058 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:4][C:3]=1[CH3:12].[NH3:13]>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:7]=[C:6]([S:8](=[O:10])(=[O:9])[NH2:13])[CH:5]=[CH:4][C:3]=1[CH3:12]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 2597442-Chloro-p-toluenesulfochloride

Product 1

HCID 2568113-Chloro-P-toluenesulfonamide

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

8 g of 2-chloro-toluene-4-sulfonic acid chloride is dissolved in 25 ml of CHCl3 and slowly stirred into 100 ml of concentrated NH3 solution. After 10 minutes of stirring at room temperature, the solution is concentrated by evaporation to one-half of its original volume. The substance is suctioned off, washed with water and dried. 2-Chloro-4-sulfamoyltoluene is obtained.

Workup

  1. concentrationthe solution is concentrated by evaporation to one-half of its original volume
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-153abf42e7bf47b8a531f4931c830821
Source dataset
uspto-grants-2009_05
Patent number
US07534780B2

Linked notes

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