N-Methyl-tert-butylamine → 4-(2-{2-[Tert-butyl(methyl)amino]ethyl}-1-benzofuran-5-yl)benzonitrile

HRID 494774

Reaction equation

HRID 494774 reaction equation
CS(O[CH2:6][CH2:7][C:8]1[O:9][C:10]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][C:20]([C:23]#[N:24])=[CH:19][CH:18]=3)=[CH:13][C:11]=2[CH:12]=1)(=O)=O.[C:25]([NH:29][CH3:30])([CH3:28])([CH3:27])[CH3:26]>>[C:25]([N:29]([CH3:30])[CH2:6][CH2:7][C:8]1[O:9][C:10]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][C:20]([C:23]#[N:24])=[CH:19][CH:18]=3)=[CH:13][C:11]=2[CH:12]=1)([CH3:28])([CH3:27])[CH3:26]

Participants

3

Reactant 2

HCID 84552N-Methyl-tert-butylamineHCID 113936782-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl Methanesulfonate

Product 1

HCID 99021534-(2-{2-[Tert-butyl(methyl)amino]ethyl}-1-benzofuran-5-yl)benzonitrile

Procedure

The product from Example 1C and tert-butyl(methyl)amine were processed as described in Example 1D to provide the titled compound. MS (DCI) m/z 333 (+H)+;

Sources & evidence

ORD record
ord-917f4bd311514517b9b8281539cfadaf
Source dataset
uspto-grants-2009_05
Patent number
US07538138B2

Linked notes

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