HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → [4-(1,4-Benzodioxan-5-yl)-1,2,3,6-tetrahydropyrid-1-yl]acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | 4-[(1,4-Benzodioxan-5-yl)]-1,2,3,6-tetrahydropyridine hydrochloride | HCID 19096238 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | [4-(1,4-Benzodioxan-5-yl)-1,2,3,6-tetrahydropyrid-1-yl]acetonitrile | HCID 19105274 | — |
Reaction Steps
2.5 g of potassium carbonate and, dropwise, a solution of 1.08 g of bromoacetonitrile in 10 ml of acetone are added to a solution of 1.9 g of the amine hydrochloride obtained in Stage B in 40 ml of acetone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05242933 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-8836235aef454333bcb8b379cc7831d3 |
| Source note | uspto-grants-1993_09 |