HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-ethoxypyridine → 4-Chloro-3,8-dimethyl-1-(6-ethoxy-2-pyridinyl)-1H-pyrazolo[3,4-b]quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-ethoxypyridine | HCID 98563 | — |
| Reactant | 8-methyl-2-(2-oxopropyl)-4H-3,1-benzoxazin-4-one | HCID 22320304 | — |
| Reactant | 6-Ethoxy-2-hydrazinopyridine | HCID 22320339 | — |
| Product | 4-Chloro-3,8-dimethyl-1-(6-ethoxy-2-pyridinyl)-1H-pyrazolo[3,4-b]quinoline | HCID 22320216 | — |
Reaction Steps
Following the procedures described in Reference Example 2-3 and Example 2-1, the title compound was prepared from 8-methyl-2-(2-oxopropyl)-4H-3,1-benzoxazin-4-one and 6-ethoxy-2-hydrazinopyridine which was previously prepared from 2-chloro-6-ethoxypyridine following the method described in Reference Example 2-2 (62% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949648B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-1aefef6cc08e4a6b8a063a3d8c9ab28f |
| Source note | uspto-grants-2005_09 |