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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4982Generated: October 26, 2026

Boc-Leu-Ala-OBzl → H-Leu-Ala-OBzl

https://huagongshe.com/reaction/4982

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoc-Leu-Ala-OBzlHCID 58901353—
SolventTrifluoroacetic acidHCID 6422—
ProductH-Leu-Ala-OBzlHCID 16742166—
ProductBoc-Leu-Ala-OBzlHCID 58901353—

Reaction Steps

Boc-Leu-Ala-OBzl was prepared by the procedure for dipeptide synthesis in Example 2. Boc-Leu-Ala-OBzl (23.7 g, 57.7 mmoles) was dissolved in 40 mL of anhydrous trifluoroacetic acid. After 15 min, excess trifluoroacetic acid was removed by evaporation and the residue was treated with ether to yield H-Leu-Ala-OBzl.trifluoroacetic acid as a crystalline product (22.8 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05242904
Source datasetuspto-grants-1993_09
ORD IDord-d330762a78a24610a29680bec14ad834
Source noteuspto-grants-1993_09