HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Leucine, N-((1,1-dimethylethoxy)carbonyl)- → Boc-Leu-Gly-Leu-Ala-OBzl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Leucine, N-((1,1-dimethylethoxy)carbonyl)- | HCID 83170 | — |
| Reactant | H-Gly-Leu-Ala-OBzl | HCID 131717745 | — |
| Product | Boc-Leu-Gly-Leu-Ala-OBzl | HCID 131717746 | — |
Reaction Steps
Boc-Leu-Gly-Leu-Ala-OBzl was prepared by coupling Boc-Leu-OH (2.62 g, 10.5 mmoles) to H-Gly-Leu-Ala-OBzl using the mixed anhydride procedure described in Example 2. The resulting product was crystallized from ethyl acetate:hexane to yield 2.7 g (mp 95°-96°) in the first crop.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05242904 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-dcb3efb5c2714b649c6024418e3d449a |
| Source note | uspto-grants-1993_09 |