HCID 178455807, compound → HCID 178455808, compound

HRID 501286

Reaction equation

HRID 501286 reaction equation
[CH2:1]([C@H:3]1[CH2:8][CH2:7][C@H:6]([NH:9][C:10]([C@@H:12]2[CH2:14][C@H:13]2[CH2:15][OH:16])=[O:11])[CH2:5][CH2:4]1)[CH3:2].C[C@H]1CC[C@H](NC([C@@H]2C[C@H]2C[O:31][S:32]([CH3:35])(=O)=[O:33])=O)CC1>>[CH2:1]([C@H:3]1[CH2:4][CH2:5][C@H:6]([NH:9][C:10]([C@@H:12]2[CH2:14][C@H:13]2[CH2:15][O:16][S:32]([CH3:35])(=[O:33])=[O:31])=[O:11])[CH2:7][CH2:8]1)[CH3:2]

Participants

3

Reactant 2

HCID 178455807HCID 178455807, compoundHCID 178505300HCID 178505300, compound

Product 1

HCID 178455808HCID 178455808, compound

Procedure

Follow the procedure of Example 11d, and substitute trans-2-hydroxymethyl-cyclopropanecarboxylic acid trans-(4-ethylcyclohexyl)-amide, Example 13c for methane sulfonic acid 2-(trans-4-methyl-cyclohexylcarbamoyl)-trans-cyclopropylmethyl ester therein, to obtain the title compound, m/z=304 (M+H)+.

Sources & evidence

ORD record
ord-092a2679bd924091b6e29caa8d7e9dd2
Source dataset
uspto-grants-2010_08
Patent number
US07772252B2

Linked notes

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