Thiazole, 2-(phenylthio)- → 5-Bromo-2-chloro-4-[2-(phenylthio)thiazol-5-yl]pyrimidine

HRID 507603Notes

Reaction equation

HRID 507603 reaction equation
[C:1]1([S:7][C:8]2[S:9][CH:10]=[CH:11][N:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:13][C:14]1[CH:15]=[N:16][C:17]([Cl:20])=[N:18][CH:19]=1>>[Br:13][C:14]1[C:15]([C:10]2[S:9][C:8]([S:7][C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[N:12][CH:11]=2)=[N:16][C:17]([Cl:20])=[N:18][CH:19]=1

Participants

3

Reactant 2

HCID 606073Thiazole, 2-(phenylthio)-HCID 6066655-Bromo-2-chloropyrimidine

Product 1

HCID 574288405-Bromo-2-chloro-4-[2-(phenylthio)thiazol-5-yl]pyrimidine

Procedure

The title compound was prepared from 2-Phenylthiothiazole and 5-bromo-2-chloro-pyrimidine in a manner analogous to Example 249, Step 1. MS (M+H)+ 386.

Sources & evidence

ORD record
ord-120a789a56d64386b59fb4ef88c21080
Source dataset
uspto-grants-2010_08
Patent number
US07786132B2

Reaction notes

Loading…