HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cinnamoyl Chloride → (E)-1-(2-pyridyl)-2-styryl-5-trifluoromethyl-1H-benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cinnamoyl Chloride | HCID 5354261 | — |
| Reactant | (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole | HCID 9796241 | — |
| Reactant | 1,2-Benzenediamine, N1-2-pyridinyl-4-(trifluoromethyl)- | HCID 22736707 | — |
| Product | (E)-1-(2-pyridyl)-2-styryl-5-trifluoromethyl-1H-benzimidazole | HCID 22736704 | — |
Reaction Steps
The titled compound was prepared from 2-amino-N-(2-pyridyl)-4-trifluoromethylaniline and (E)-cinnamoyl chloride according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method A). MW: 365.36; mp: 144.5-145.0° C.; 1H-NMR (CDCl3) δ: 8.82-8.79 (1H, m), 8.12-8.00 (3H, m), 7.57-7.49 (6H, m), 7.41-7.31 (3H, m), 7.11 (1H, d, J=16.1 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06713482B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-c279e940d9c348c6bcfc93b425d76415 |
| Source note | uspto-grants-2004_03 |