2-Methyl-1-pentanol → 2-Methyl-1-pentyl methanesulfonate

HRID 50975

Reaction equation

[CH3:1][CH:2]([CH2:5][CH2:6][CH3:7])[CH2:3][OH:4].[CH3:8][S:9](Cl)(=[O:11])=[O:10]>>[CH3:8][S:9]([O:4][CH2:3][CH:2]([CH3:1])[CH2:5][CH2:6][CH3:7])(=[O:11])=[O:10]

Participants

Reactant 2

HCID 77452-Methyl-1-pentanol

HCID 31297Methanesulfonyl chloride

Product 1

HCID 224867612-Methyl-1-pentyl methanesulfonate

Procedure

The title compound was prepared by following the general procedure of Example 43 for mesylation as a colorless oil (856 mg, 89%) from 2-methyl-1-pentanol (497 mg, 4.90 mmol) and methanesulfonyl chloride (821 mg, 7.30 mmol). 1H NMR (CDCl3, 300 MHz) δ0.89-0.93 (m, 3H), 0.98 (d, 3H, J=6.6 Hz), 1.15-1.43 (m, 4H), 1.88-1.90 (m, 1H), 3.00 (s, 3H), 3.98-4.11 (m, 2H) ppm.

Sources & evidence

ORD record: ord-d79780d30ecc47f799ce5e10fbff2fe1
Source dataset: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06713471B1

Linked notes

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